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| Uprima Uprima is new drug for the treatment of erectile dysfunction. It is a sublingual medication and was the first centrally acting oral therapy for ED on the market. Uprima sublingual dissolves immediately when placed under the tongue. Detectable plasma concentrationa occur within 10 minutes. Uprima works by stimulating dopamine receptors in the hypothalamus and mid-brain, enhancing the natural erection process. It causes a signal to be transmitted down the spinal cord to the sacral parasympathetic nucleus where it stimulates parasympathetic activity of the sacral nerves supplying the penis. As a result, the penile smooth muscles relax, the penile arteries dilate and the penis becomes erect. Median time to onset of erection for Uprima is 18-19 minutes. 34% of erections occured within 10 minutes and 71% of erections occured within 20 minutes. Side effects of Uprima: These include:- headache, nausea and dizziness. Nausea is generally mild to moderate in nature, declining with continued use. Other adverse side effects include: infection; pain; flushing; taste disorder; sweating; yawning; rhinitus; pharyngitis, somnolence, increased cough. However, such side effects tend to be mild and short-lived. Uprima does not produce an instant erection and much like Viagra sexual stimulation is generally required. Uprima is dispensed in blister packs of four and comes in 2mg and 3mg dosage. Patients generally start on the 2mg dose and increase to 3mg on subsequent administrations if rquired. There is additional information here:- Uprima You can order Uprima from:- Medix24 PharmaExpressRX Get Pharma |